Q2 Newsletter

Portfolio comapny highlights

S4 Medical Corp Launches Atrial Fibrillation Esophageal
Protection Device Following FDA Clearance

U.S. Food and Drug Administration for its redesigned esolution® esophageal deviation device, has begun its commercial launch starting in the United States. S4 has the first and only FDA approved device to prevent ablation-related esophageal injury using any catheter ablation modality. The company received an FDA De Novo grant in September 2023, but then optimized the device for manufacturability, improved workflow, and enhanced usability, which concluded in attainment of FDA 510(k) clearance in November 2024.

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Partner Highlights

YBI and XJet Grow Partnership with Metal AM System

​XJet reports that Youngstown Business Incubator (YBI) has acquired a Carmel 1400M Metal additive manufacturing (AM) solution. The system will be housed at Humtown Products, a YBI partner and America Makes member. This latest acquisition builds on the capabilities of the XJet Carmel 1400C ceramic system installed in 2018, expanding YBI's metal production capabilities to serve industries including aerospace and defense, medical devices, and electronics in North America.

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Industry Highlights

The Resilient Venture Capital Landscape: Trends And Outlooks For 2025

Artificial intelligence defined venture capital in 2024, showing up often and everywhere. But there were other signs of optimism that also boosted the industry, including crypto’s resurgence and the secondary market boom. Throughout the year, the pipeline of pre-IPO companies continued to expand, and strong VC performance made the case for investing in top quartile, established venture funds.

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